Goose.

Prophylactic cranial irradiation (PCI) is still the standard for limited stage small cell lung cancer (LS-SCLC), at least until MAVERICK reports at the end of the decade, although there is now a “consider MRI brain surveillance” caveat in the NCCN algorithm. In the meantime, here’s a small series from Henry Ford looking at the last 14 patients treated with SBRT or surgery typically followed by chemo for T1-2N0 LS-SCLC. The point is that none of them got PCI and none have evidence of brain mets on close interval surveillance MRI at a median of 14 months (range 2.4 months to over 5 years). | Khatib, Adv Radiat Oncol 2023