None the WISER.

In the WISER study, over 350 breast cancer survivors receiving standard lymphedema therapy were randomized to receive 1) no additional intervention, 2) a home-based exercise program, 3) a diet intervention, or 4) a home-based diet and exercise program. The goal was to determine if weight loss improved lymphedema outcomes. Despite significant weight loss in the diet and combination groups, there was surprisingly no difference in any lymphedema outcomes. | Schmitz, JAMA Oncol 2019