Transforming.

This commentary may fall short of that description, but it’s still a good refresher on the little we know and the lot we don’t about identifying patients with clonal hematopoiesis who will transform to frank leukemia. We’ve made some headway on identifying high-risk genes, such as ASXL1 and TET2, but without clinically-applicable ways to target them. | Karlsson, N Engl J Med 2018