Sore arm?
Enter a one-sniff nasal spray as the solution to flu (etc?) vaccine efficacy. Early testing of using live adenoviruses as a replicating vector to present influenza surface glycoproteins, specifically and intentionally at the same mucosal site as the target virus (i.e., nasal mucosa), has demonstrated successful induction of high levels of long-lasting local and systemic flu-specific neutralizing antibodies. | Matsuda, J Clin Invest 2021
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