Coffee cleanse.

This cohort study looked at 1171 patients with advanced or metastatic colorectal cancer who were enrolled in the randomized SWOG 80405 trial. These authors found that increased consumption of coffee at the time of enrollment was associated with a lower risk of disease progression and death. Interestingly, this association seemed to be dose dependent (i.e. more cups per day had greater protective effect) Additionally, significant positive associations were found in patients consuming both caffeinated as well as decaf coffee. | Mackintosh, JAMA Oncol 2020