Up the ante.

Ten-year results of the Japanese phase 2 JCOG0403 assessing lung SBRT for 64 patients with early-stage operable lung cancers demonstrates 9 local (14%), 11 (17%) regional and 11 (17%) distant failures. That’s good but not great leading to the phase 3 JCOG 1408 comparing this regimen of roughly 10.5 Gy x 4 to the more aggressive 13.75 Gy x 4. | Nagata, Int J Radiat Oncol Biol Phys 2018