Chemo folli.

Chemo remains firmly seated on the struggle bus to stay relevant in the new era of targeted therapy. Treatment for advanced-stage, low grade follicular lymphoma is generally deferred. When you do decide to treat, conventional first-line treatment is chemo-immunotherapy. Nowadays, some are starting with chemo-free regimens. From long-term results of two Nordic trials we learn that rituximab-only up-front approaches have long-term overall survival outcomes comparable to regimens including chemotherapy. TBL: Patients with advanced-stage follicular lymphoma may do well with a chemo-free treatment approach. | Lockmer, J Clin Oncol 2018