Antiviral therapy.

Still not a big fan of infecting folks with viruses to cure cancer? Then this study is for you. It describes a non-viral CRISPR system for genome editing involving electroporation of both the cells of interest and the CRISPR ribonucleoprotein. Efficient targeted uptake of genes was successfully completed virus-free, which is great. They then took it a step further by using this method to edit the T-cell receptor, showcasing the huge impact this technology could have on making CAR-T cell manufacturing easier and, that’s right, cheaper. | Roth, Nature 2018